Biomaterials for mRNA delivery
Author:
Affiliation:
1. Laboratory for Nanoengineering & Drug Delivery
2. Brigham and Women's Hospital
3. Harvard Medical School
4. Boston
5. USA
6. Vascular Biology Program
7. Boston Children's Hospital
Abstract
Schematic representation of various biomaterial-based systems for mRNA delivery: (a) protamine–mRNA complex; (b) lipid nanoparticle; (c) lipid nanoparticle with inorganic compounds (e.g.apatite); (d) cationic polymeric nanoparticle; (e) lipid–polymer hybrid nanoparticles including (i) mRNA–polymer complex core surrounded by a lipid shell and (ii) polymer core surrounded by a lipid shell with mRNA absorbed onto the surface; and (f) gold nanoparticle.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2015/BM/C5BM00198F
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