Visualization of size-dependent tumour retention of PEGylated nanographene oxide via SPECT imaging

Author:

Cao Tianye12345,You Peihong12345,Zhou Xiaobao12345,Luo Jianmin12345,Xu Xiaoping12345,Zhou Zhiguo678910,Yang Shiping678910,Zhang Yingjian12345,Yang Hong678910,Wang Mingwei12345

Affiliation:

1. Department of Nuclear Medicine

2. Fudan University Shanghai Cancer Center

3. Department of Oncology

4. Shanghai Medical College

5. Fudan University

6. The Key Laboratory of Resource Chemistry of Ministry of Education

7. Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors

8. Shanghai Normal University

9. Shanghai 200234

10. China

Abstract

Sub-50 nm usNGO–PEG was confirmed to be the favorable size for faster and higher cellular uptake and efficient tumor accumulation than over-50 nm NGO–PEG.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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