Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions-Reference-Cited by-同舟云学术

Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions

Published:2015 Issue:45 Volume:13 Page:11052-11071
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ovadia Reuben¹²³⁴⁵,Lebrun Aurélien⁶⁷⁸⁹¹⁰,Barvik Ivan¹¹¹²¹³¹⁴¹⁵,Vasseur Jean-Jacques⁶⁷¹⁶⁹¹⁰,Baraguey Carine⁶⁷¹⁶⁹¹⁰,Alvarez Karine¹²³⁴⁵

Affiliation:

1. Laboratoire d'Architecture et Fonction des Macromolécules Biologiques

2. Université Aix-Marseille UMR CNRS 7257

3. Equipe “Antiviral Medicinal Chemistry”

4. Parc scientifique de Luminy

5. 13288 Marseille Cedex 9

6. Institut des Biomolécules Max Mousseron (IBMM)

7. UMR 5247 CNRS - Université Montpellier-ENSCM

8. Laboratoire de Mesures Physiques - Plateau Technique

9. 34095 Montpellier Cedex 5

10. France

11. Institute of Physics

12. Faculty of Mathematics and Physics

13. Charles University

14. Prague 2

15. Czech Republic

16. Equipe “Oligonucléotides Modifiés”

Abstract

A solution phase synthesis of peptide nucleic acid monomers and dimers was developed by using microwave-promoted Ugi multicomponent reactions.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01604E

Reference57 articles.

1. 3′-Deoxy Phosphoramidate Dinucleosides as Improved Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity

2. Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors

3. Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

4. Peptide nucleic acids: a review on recent patents and technology transfer

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