Enzymatic kinetic resolution of internal propargylic diols. Part I: a new approach for the synthesis of (S)-pent-2-yn-1,4-diol, a natural product from Clitocybe catinus-Reference-Cited by-同舟云学术

Enzymatic kinetic resolution of internal propargylic diols. Part I: a new approach for the synthesis of (S)-pent-2-yn-1,4-diol, a natural product from Clitocybe catinus

Published:2015 Issue:23 Volume:13 Page:6458-6462
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ferreira Jeiely G.¹²³⁴,Princival Cleverson R.¹⁵⁶⁷⁴,Oliveira Dyego M.¹²³⁴,Nascimento Renata X.¹²³⁴,Princival Jefferson L.¹²³⁴

Affiliation:

1. Departamento de Química Fundamental

2. Universidade Federal de Pernambuco - UFPE

3. Recife

4. Brasil

5. Instituto de Química

6. Universidade de São Paulo-USP

7. São Paulo

Abstract

An efficient two round EKR of bis-substituted propargylic diols has been described and applied for synthesize (S)-pent-2-yn-1,4-diol, a natural product from Clitocybe catinus.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00386E

Reference38 articles.

1. Chiral alkynylcarbinols from marine sponges: asymmetric synthesis and biological relevance

2. Marine natural products

3. A New C-20 Polyacetylene from the Sponge Callyspongia pseudoreticulata