Unravelling the role of amino acid sequence order in the assembly and function of the amyloid-β core-Reference-Cited by-全球学者库

Unravelling the role of amino acid sequence order in the assembly and function of the amyloid-β core

Published:2019 Issue:59 Volume:55 Page:8595-8598
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Bera Santu¹²³⁴⁵^ORCID,Arad Elad⁶⁷⁸⁵,Schnaider Lee¹²³⁴⁵,Shaham-Niv Shira¹²³⁴⁵^ORCID,Castelletto Valeria⁹¹⁰¹¹¹²,Peretz Yossef⁶⁷⁸⁵,Zaguri Dor¹²³⁴⁵,Jelinek Raz⁶⁷⁸⁵^ORCID,Gazit Ehud¹²³⁴⁵^ORCID,Hamley Ian W.⁹¹⁰¹¹¹²^ORCID

Affiliation:

1. Department of Molecular Microbiology and Biotechnology

2. George S. Wise Faculty of Life Sciences

3. Tel Aviv University

4. Tel Aviv 69978

5. Israel

6. Department of Chemistry & Ilse Katz Institute (IKI) for Nanoscale Science and Technology

7. Ben Gurion University of the Negev

8. Beer Sheva 8410501

9. Department of Chemistry

10. University of Reading

11. Reading RG6 6AD

12. UK

Abstract

Here we report the influence of amino acid sequence order on the self-assembly and biological functions of the core recognition motif of Amyloid β.

Funder

H2020 European Research Council

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC03654G

Reference33 articles.

1. Structural and kinetic features of amyloid β-protein fibrillogenesis

2. Resolving controversies on the path to Alzheimer's therapeutics

3. Protein Misfolding, Functional Amyloid, and Human Disease

4. The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

5. Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aggregation and partitioning of amyloid peptide fragments in the presence of a lipid bilayer: A coarse grained molecular dynamics study;Biophysical Chemistry;2023-09

2. Catalytic amyloids;Trends in Chemistry;2022-10

3. Cholesterol as a key player in amyloid β-mediated toxicity in Alzheimer’s disease;Frontiers in Molecular Neuroscience;2022-08-25

4. Structure and Conservation of Amyloid Spines From the Candida albicans Als5 Adhesin;Frontiers in Molecular Biosciences;2022-07-06

5. Does the inclusion of electronic polarisability lead to a better modelling of peptide aggregation?;RSC Advances;2022