Efficient and stereoselective one-pot synthesis of benzo[b]oxazolo[3,4-d][1,4]oxazin-1-ones
Author:
Affiliation:
1. Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation
2. Institute of Materia Medica
3. Peking Union Medical College
4. Chinese Academy of Medical Sciences
5. Beijing 100050
Abstract
An efficient and mild one-pot convergent synthesis protocol has been developed for benzo[b]oxazolo[3,4-d][1,4]oxazin-1-one derivatives through the Mitsunobu reaction and sequential cyclization.
Funder
National Natural Science Foundation of China
National Major Science and Technology Projects of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA04104A
Reference17 articles.
1. The oxazolidinones: past, present, and future
2. Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent
3. Discovery of the Novel Antithrombotic Agent 5-Chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): An Oral, Direct Factor Xa Inhibitor
4. Design, Synthesis, and Structure–Activity Relationship Studies of Highly Potent Novel Benzoxazinyl-Oxazolidinone Antibacterial Agents
5. Synthesis and biological evaluation of novel benzoxazinyl-oxazolidinones as potential antibacterial agents
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