Intestinal toxicity alleviation and efficacy potentiation through therapeutic administration of Lactobacillus paracasei GY-1 in the treatment of gout flares with colchicine

Author:

Zeng Jiaqi1,Li Yan1,Zou Yizhi1,Yang Ying2,Yang Tingting1,Zhou Yizhuang1ORCID

Affiliation:

1. Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin, Guangxi 541199, China

2. Department of Public Health, School of Medicine, Guangxi University of Science and Technology, Liuzhou, Guangxi 545005, China

Abstract

The therapeutic administration of Lactobacillus paracasei GY-1 attenuates the physical, behaviral, and intestinal toxicity of colchicine, and enhances the therapeutic effect for gout flares when combined with colchicine.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

National College Students Innovation and Entrepreneurship Training Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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