In vitro AMPK activating effect and in vivo pharmacokinetics of mogroside V, a cucurbitane-type triterpenoid from Siraitia grosvenorii fruits-Reference-Cited by-同舟云学术

In vitro AMPK activating effect and in vivo pharmacokinetics of mogroside V, a cucurbitane-type triterpenoid from Siraitia grosvenorii fruits

Published:2016 Issue:9 Volume:6 Page:7034-7041
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Luo Zuliang¹²³⁴⁵,Qiu Feng⁶⁷⁸⁹⁵,Zhang Kailun¹²³⁴⁵,Qin Xijun¹²³⁴⁵,Guo Yuhua¹²³⁴⁵,Shi Hongwu¹²³⁴⁵,Zhang Lixia¹⁰²¹¹⁵,Zhang Zhonglian¹⁰²¹¹⁵,Ma Xiaojun¹²³⁴⁵

Affiliation:

1. Institute of Medicinal Plant Development

2. Chinese Academy of Medical Sciences

3. Peking Union Medical College

4. Beijing 100193

5. China

6. Beijing Key Lab of TCM Collateral Disease Theory Research

7. School of Traditional Chinese Medicine

8. Capital Medical University

9. Beijing

10. Yunnan Branch Institute of Medicinal Plant Development

11. Jinghong 530023

Abstract

The aim of this study was to explore the anti-diabetic effects of mogroside V (MV) and its aglycone mogrol (MO), both isolated from the fruits of Siraitia grosvenorii Swingle, and to investigate the pharmacokinetic behaviors of MV and its metabolite MO in rats.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA23275A

Reference30 articles.

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4. Novel Small-Molecule AMP-Activated Protein Kinase Allosteric Activator with Beneficial Effects in db/db Mice

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