Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells-Reference-Cited by-同舟云学术

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Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells

Published:2017 Issue:29 Volume:9 Page:10327-10334
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Papi M.¹²³⁴,Caputo D.⁵⁶⁴,Palmieri V.¹²³⁴,Coppola R.⁵⁶⁴^ORCID,Palchetti S.⁷⁸⁹⁴¹⁰^ORCID,Bugli F.¹¹¹²³⁴,Martini C.¹¹¹²³⁴,Digiacomo L.⁷⁸⁹⁴¹³,Pozzi D.⁷⁸⁹⁴¹⁰^ORCID,Caracciolo G.⁷⁸⁹⁴^ORCID

Affiliation:

1. Istituto di Fisica

2. Università Cattolica del Sacro Cuore

3. 00168 Rome

4. Italy

5. University Campus Bio-Medico di Roma

6. 00128 Rome

7. Department of Molecular Medicine

8. “Sapienza” University of Rome

9. 00161 Rome

10. Istituti Fisioterapici Ospitalieri

11. Istituto di Microbiologia

12. Universitá Cattolica del Sacro Cuore

13. Department of Bioscience and Biotechnology

Abstract

The protein corona boosts the cellular uptake of clinically approved PEGylated lipid nanoparticles in pancreas ductal adenocarcinoma cells.

Funder

Ministero della Salute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NR/C7NR03042H

Reference66 articles.

1. Liposomal drug delivery systems: From concept to clinical applications

2. Liposome-like nanostructures for drug delivery

3. New-concept chemotherapy by nanoparticles of biodegradable polymers: where are we now?

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