Pro-apoptotic genes as new targets for single and combinatorial treatments with resveratrol and curcumin in colorectal cancer

Author:

Gavrilas Laura Ioana1234ORCID,Cruceriu Daniel56748ORCID,Ionescu Corina19104,Miere Doina1234ORCID,Balacescu Ovidiu811124ORCID

Affiliation:

1. University of Medicine and Pharmacy “Iuliu Hatieganu”

2. Department of Bromatology

3. Cluj-Napoca 400337

4. Romania

5. “Babes-Bolyai” University

6. Department of Molecular Biology and Biotechnology

7. Cluj-Napoca 400006

8. The Oncology Institute “Prof. Dr. Ion Chiricuta” Department of Functional Genomics

9. Department of Pharmaceutical Biochemistry and Clinical Laboratory

10. Cluj-Napoca 400349

11. Proteomics and Experimental Pathology

12. Cluj-Napoca 400015

Abstract

Colorectal cancer (CRC) represents the third most diagnosed type of cancer worldwide with high mortality and an increased incidence rate.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Reference58 articles.

1. American Cancer Society , Global Cancer Facts & Figures , 3rd edn, 2015 , https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/global-cancer-facts-and-figures/global-cancer-facts-and-figures-3rd-edition.pdf (accessed December 2018)

2. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

3. Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010

4. Hallmarks of Cancer: The Next Generation

5. Apoptosis in cancer: from pathogenesis to treatment

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