Coumarin-substituted 1,2,4-triazole-derived silver(i) and gold(i) complexes: synthesis, characterization and anticancer studies-Reference-Cited by-同舟云学术

Coumarin-substituted 1,2,4-triazole-derived silver(i) and gold(i) complexes: synthesis, characterization and anticancer studies

Published:2019 Issue:3 Volume:43 Page:1216-1229
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Achar Gautam¹²³⁴^ORCID,C. R. Shahini¹²³⁴,Patil Siddappa A.¹²³⁴^ORCID,Małecki Jan Grzegorz⁵⁶⁷⁸⁹,Budagumpi Srinivasa¹²³⁴^ORCID

Affiliation:

1. Centre for Nano and Material Sciences

2. Jain University

3. Ramanagaram

4. India

5. Department of Crystallography

6. Institute of Chemistry

7. University of Silesia

8. 40-006 Katowice

9. Poland

Abstract

A series of coumarin-substituted 1,2,4-triazolium salts and their respective silver– and gold– N-heterocyclic carbene complexes have been reported. The complexes displayed promising anticancer activity with GI₅₀ values of up to 0.354 μM and 8.5983 μM against MCF 7 and HT-29 cell lines, respectively.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C8NJ02927J

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