Titanium carbenoid-mediated cyclopropanation of allylic alcohols: selectivity and mechanism-Reference-Cited by-同舟云学术

Titanium carbenoid-mediated cyclopropanation of allylic alcohols: selectivity and mechanism

Published:2015 Issue:22 Volume:13 Page:6325-6332
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Durán-Peña M. J.¹²³⁴⁵,Botubol-Ares J. M.¹²³⁴⁵,Hanson J. R.⁶⁷⁸⁹,Hernández-Galán R.¹²³⁴⁵^ORCID,Collado I. G.¹²³⁴⁵

Affiliation:

1. Departamento de Química Orgánica

2. Facultad de Ciencias

3. Campus Universitario Río San Pedro s/n

4. Torre sur

5. 4° planta

6. Department of Chemistry

7. University of Sussex

8. Brighton

9. UK

Abstract

A new method for the chemo- and stereoselective conversion of allylic alcohols into the corresponding cyclopropane derivatives has been developed using a titanium carbenoid. The scope, limitations and mechanism are discussed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00544B

Reference80 articles.

1. Fascinating Natural and Artificial Cyclopropane Architectures

2. Cyclopropane Derivatives and their Diverse Biological Activities

3. Intermolecular Metal-Free Cyclopropanation of Alkenes Using Tosylhydrazones

4. Transition-Metal-Catalyzed Cyclopropanation of Nonactivated Alkenes in Dibromomethane with Triisobutylaluminum

5. Heterocycles from cyclopropanes: applications in natural product synthesis

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