Bis-indolylation of aldehydes and ketones using silica-supported FeCl3: molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding sites-Reference-Cited by-同舟云学术

Bis-indolylation of aldehydes and ketones using silica-supported FeCl3: molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding sites

Published:2021 Issue:49 Volume:11 Page:30827-30839
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Deb Barnali¹^ORCID,Debnath Sudhan²^ORCID,Chakraborty Ankita¹^ORCID,Majumdar Swapan¹^ORCID

Affiliation:

1. Department of Chemistry, Tripura University, Suryamaninagar, 799 022, India

2. Department of Chemistry, Netaji Subhash Mahavidalaya, Tripura, 799114, India

Abstract

Silica supported FeCl3 catalyzed simple protocol for the synthesis of bis-indolylmethanes was explored via grindstone chemistry. Synthesized compounds were screened virtually as inhibitor by targeting the binding site of SARS-CoV-2 main protease enzyme.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05679D

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