Design and optimization of lipid-modified poly(amidoamine) dendrimer coated iron oxide nanoparticles as probes for biomedical applications

Author:

Boni A.123,Bardi G.145,Bertero A.67891,Cappello V.123,Emdin M.1011,Flori A.1011,Gemmi M.123,Innocenti C.121314,Menichetti L.10111511,Sangregorio C.1617,Villa S.123,Piazza V.123

Affiliation:

1. Istituto Italiano di Tecnologia

2. Center for Nanotechnology Innovation @NEST

3. 56127 Pisa, Italy

4. Center for Biomolecular Nanotechnologies @UniLe

5. 73010 Arnesano (Lecce), Italy

6. University of Pisa

7. Department of Biology

8. Unit of Cell and Developmental Biology

9. 56126 Pisa, Italy

10. Fondazione CNR/Regione Toscana G. Monasterio

11. 56124 Pisa, Italy

12. INSTM and Department of Chemistry “Ugo Schiff”

13. University of Florence

14. Firenze, Italy

15. CNR Institute of Clinical Physiology

16. CNR-ISTM and INSTM

17. 20133 Milano, Italy

Abstract

Superparamagnetic iron oxide nanoparticles with a wide size range (2.6–14.1 nm) were synthesized and coated with the amphiphilic poly(amidoamine) PAMAM-C12 dendrimer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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