Photo-triggered Zn2+ release for the regulation of zinc enzymes

Author:

Zhang Minjie12345,Jia Yongguang12345ORCID,Gao Meng12345ORCID,Ren Li12345ORCID,Tang Ben Zhong67895ORCID

Affiliation:

1. National Engineering Research Center for Tissue Restoration and Reconstruction

2. Key Laboratory of Biomedical Engineering of Guangdong Province

3. Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education

4. Innovation Center for Tissue Restoration and Reconstruction

5. South China University of Technology

6. AIE Institute

7. Center for Aggregation-Induced Emission

8. Key Laboratory of Luminescence from Molecular Aggregates of Guangdong Province

9. State Key Laboratory of Luminescent Materials and Devices

Abstract

A photo-triggered Zn2+ release system was developed based on HBTH–Zn–TAT NPs, which showed an excellent light-dependent “on–off” performance for Zn2+ release and the precise regulation of extra- and intracellular zinc enzyme activities.

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

National Key Research and Development Program of China

Pearl River S and T Nova Program of Guangzhou

Fundamental Research Funds for the Central Universities

Innovation and Technology Commission - Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

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