Nanoconjugation prolongs endosomal signaling of the epidermal growth factor receptor and enhances apoptosis
Author:
Affiliation:
1. Department of Chemistry and The Photonics Center
2. Boston University
3. Boston, USA
Abstract
EGF nanoconjugation and its effect on trafficking, endosomal signaling and ligand-mediated apoptosis was investigated.
Funder
National Cancer Institute
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2016/NR/C6NR02974D
Reference92 articles.
1. Nanoconjugation: a materials approach to enhance epidermal growth factor induced apoptosis
2. The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies
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4. Inhibiting EGFR Clustering and Cell Proliferation with Gold Nanoparticles
5. Protein Coronas on Gold Nanorods Passivated with Amphiphilic Ligands Affect Cytotoxicity and Cellular Response to Penicillin/Streptomycin
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