Injectable cationic hydrogels with high antibacterial activity and low toxicity-Reference-Cited by-同舟云学术

Injectable cationic hydrogels with high antibacterial activity and low toxicity

Published:2016 Issue:36 Volume:7 Page:5620-5624
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Du Hong¹²³⁴⁵,Wang Ying¹²³⁴⁵,Yao Xuxia⁶³⁴⁵,Luo Qiaojie⁷⁸⁹³¹⁰,Zhu Weipu¹²³⁴⁵,Li Xiaodong⁷⁸⁹³¹⁰,Shen Zhiquan¹²³⁴⁵

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization

2. Department of Polymer Science and Engineering

3. Zhejiang University

4. Hangzhou 310027

5. People's Republic of China

6. School of Materials Science and Engineering

7. Department of Oral and Maxillofacial Surgery

8. Affiliated Stomatology Hospital

9. School of Medicine

10. Hangzhou 310006

Abstract

We prepared injectable cationic hydrogels with strong antibacterial activity and remarkably low toxicity by in situ thiol–ene “click” reaction between dimethacrylate terminated poly(hexamethylene guanidine) (PHMGDMA) and poly[oligo(ethylene) glycol mercaptosuccinate] (POEGMS) under physiological conditions.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PY/C6PY01346E

Reference41 articles.

1. Injectable hydrogels as unique biomedical materials

2. Designing Injectable, Covalently Cross-Linked Hydrogels for Biomedical Applications