Ultrasensitive recognition of AP sites in DNA at the single-cell level: one molecular rotor sequentially self-regulated to form multiple different stable conformations

Author:

Feng Beidou12345,Wang Kui12345,Yang Yonggang12345,Wang Ge678,Zhang Hua12345ORCID,Liu Yufang12345ORCID,Jiang Kai12345

Affiliation:

1. Henan Key Laboratory of Green Chemical Media and Reactions

2. Ministry of Education

3. Key Laboratory of Green Chemical Media and Reactions; Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals

4. Henan Key Laboratory of Organic Functional Molecules and Drug Innovation

5. School of Chemistry and Chemical Engineering

6. Xinxiang Medical University

7. Xinxiang 453000

8. P. R. China

Abstract

Molecular rotors self-regulate their conformations to emit different ultrasensitive recognition signals for AP sites in DNA at the single-cell level.

Funder

National Natural Science Foundation of China

Key Scientific Research Project of Colleges and Universities in Henan Province

Henan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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