Thiosemicarbazone organocatalysis: tetrahydropyranylation and 2-deoxygalactosylation reactions and kinetics-based mechanistic investigation-Reference-Cited by-同舟云学术

Thiosemicarbazone organocatalysis: tetrahydropyranylation and 2-deoxygalactosylation reactions and kinetics-based mechanistic investigation

Published:2017 Issue:12 Volume:8 Page:7978-7982
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Larsen Dennis¹²³⁴^ORCID,Langhorn Line M.¹²³⁴^ORCID,Akselsen Olivia M.¹²³⁴,Nielsen Bjarne E.¹²³⁴^ORCID,Pittelkow Michael¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Copenhagen

3. DK-2100 Copenhagen

4. Denmark

Abstract

Thiosemicarbazones are introduced as a new class of highly tunable and efficient organocatalysts. We showcase this by studies of the tetrahydropyranylation reaction, where insights to the mechanism was achieved by a double Hammett analysis of both the substrate and the catalyst.

Funder

Lundbeckfonden

Danish Council for Independent Research

University of Copenhagen

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC03366D

Reference39 articles.

1. Asymmetric Catalysis by Chiral Hydrogen-Bond Donors