Easy preparation of a liposome-mediated protein delivery system by freeze–thawing a liposome

Easy preparation of a liposome-mediated protein delivery system by freeze–thawing a liposome–protein complex

Published:2022 Issue:35 Volume:10 Page:6768-6776
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Koide Hiroyuki¹^ORCID,Ochiai Hiroki¹,Suzuki Hikaru¹,Hirata Shinya¹,Watanabe Midori¹,Yonezawa Sei¹,Dewa Takehisa²^ORCID,Oku Naoto³,Asai Tomohiro¹

Affiliation:

1. Department of Medical Biochemistry, University of Shizuoka School of Pharmaceutical Sciences, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka 422-8526, Japan

2. Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, Aichi 466-8555, Japan

3. Faculty of Pharma-Science, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan

Abstract

An easy one-step method for the encapsulation of proteins into liposomes based on freeze–thawing a protein–liposome complex was developed for efficient protein delivery.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB00271J

Reference33 articles.

1. Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

2. Homeostasis, Inflammation, and Disease Susceptibility

3. Protein therapeutics: a summary and pharmacological classification