A practical and efficient route to heteraphanes: synthesis of structurally simplified analogues of ansamycins

Author:

Reddy R. Santhosh1234,Zheng Shaojun1234,Lagishetti Chandraiah1234,You Hengyao1234,He Yun1234

Affiliation:

1. School of Pharmaceutical Sciences and Innovative Drug Research Centre

2. Chongqing University

3. Shapingba

4. P.R. China

Abstract

The intramolecular Mitsunobu reaction has been employed for the practical synthesis of a wide variety of heteraphanes. This strategy enabled the efficient synthesis of a diverse range of macrocycles with varying ring sizes under mild conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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