Kinetic modelling of an environmentally friendly carbamazepine synthesis <i>via</i> urea and iminostilbene in batch and continuous processes-Reference-Cited by-同舟云学术

Kinetic modelling of an environmentally friendly carbamazepine synthesis via urea and iminostilbene in batch and continuous processes

Published:2023 Issue:2 Volume:8 Page:402-415
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Kraus Harrison F.¹²^ORCID,Acevedo David²,Wu Wei²^ORCID,O'Connor Thomas F.²,Mohammad Adil²^ORCID,Liu Dongxia¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD 207426, USA

2. Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20993-0002, USA

Abstract

Accurate kinetic models for reaction systems allow for improved process understanding and greater quality control, which is particularly beneficial as the pharmaceutical industry shifts from batch to continuous manufacturing (CM).

Funder

Oak Ridge Institute for Science and Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RE/D2RE00409G

Reference35 articles.

1. New trends in the production of pharmaceutical granules: batch versus continuous processing

2. Continuous Processing in the Pharmaceutical Industry

3. Continuous Processing in the Manufacture of Active Pharmaceutical Ingredients and Finished Dosage Forms: An Industry Perspective

4. Microreactor Technology and Continuous Processes in the Fine Chemical and Pharmaceutical Industry: Is the Revolution Underway?

5. Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Impurity Profiling for a Scalable Continuous Synthesis and Crystallization of Carbamazepine Drug Substance;Organic Process Research & Development;2024-05-01

2. Development of a continuous synthesis process for carbamazepine using validated in-line Raman spectroscopy and kinetic modelling for disturbance simulation;Reaction Chemistry & Engineering;2023