Enantioselective synthesis of α-perfluoroalkylated prolines, their 6,7-membered homologues and derivatives
Author:
Affiliation:
1. Department of Chemistry
2. Lomonosov Moscow State University
3. Moscow
4. Russia
5. Peoples’ Friendship University of Russia
6. 117198 Moscow
7. National Research Center “Kurchatov Institute”
8. Moscow 123182
Abstract
The highly enantioselective Strecker reaction with alpha-perfluoroalkylated cyclic ketimines was reported. The corresponding asymmetric cyclic nitriles are a useful tool for obtaining amino acids and their derivatives.
Funder
Russian Foundation for Basic Research
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01223G
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