A highly efficient metal-free approach to meta- and multiple-substituted phenols via a simple oxidation of cyclohexenones-Reference-Cited by-同舟云学术

A highly efficient metal-free approach to meta- and multiple-substituted phenols via a simple oxidation of cyclohexenones

Published:2016 Issue:24 Volume:18 Page:6462-6467
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Liang Yu-Feng¹²³⁴⁵,Song Song¹²³⁴⁵,Ai Lingsheng¹²³⁴⁵,Li Xinwei¹²³⁴⁵,Jiao Ning¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs

2. School of Pharmaceutical Sciences

3. Peking University

4. Beijing 100191

5. China

Abstract

The simple and readily available I₂ catalyst, and a cheap and common DMSO oxidant could be employed for the transformation of cyclohexenones to meta- and multiple-substituted phenols with significant tolerance to various functional substituents.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/GC/C6GC02674E

Reference97 articles.

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4. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

5. C. A. Fyfe , The Chemistry of the Hydroxyl Group, Wiley-Interscience, New York, 1971

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