Metal- and additive-free radical-triggered nitration/cyclization to construct indolo[2,1-α]isoquinoline and benzimidazo[2,1-a]isoquinolin-6(5H)-one derivatives usingt-BuONO as nitro reagents

Author:

Tang Yucai1ORCID,Yang Yiting1,Zhou Qian1,Duan Jinglin1,Yang Biyu1,Du Changyuan1,He Yupeng1

Affiliation:

1. College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Hunan Provincial Key Laboratory of Water Treatment Functional Materials, Hunan Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Changde 415000, China

Abstract

An efficient metal- and additive-free nitro radical-triggered addition/cyclization for the synthesis of nitro-substituted indolo[2,1-α]isoquinoline and benzimidazo[2,1-a]isoquinolin-6(5H)-one derivatives has been developed.

Funder

Natural Science Foundation of Hunan Province

Hunan University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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