Low generation polyamine dendrimers bearing flexible tetraethylene glycol as nanocarriers for plasmids and siRNA-Reference-Cited by-同舟云学术

Low generation polyamine dendrimers bearing flexible tetraethylene glycol as nanocarriers for plasmids and siRNA

Published:2016 Issue:9 Volume:8 Page:5106-5119
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Sharma Rishi¹²³⁴,Zhang Issan⁵⁶⁷,Shiao Tze Chieh¹²³⁴,Pavan Giovanni M.⁸⁹¹⁰,Maysinger Dusica⁵⁶⁷,Roy René¹²³⁴

Affiliation:

1. Pharmaqam

2. Department of Chemistry

3. Université du Québec à Montréal

4. Montréal, Canada H3C 3P8

5. Department of Pharmacology and Therapeutics

6. McGill University

7. Montreal, Canada

8. Department of Innovative Technologies

9. University of Applied Sciences and Arts of Southern Switzerland

10. 6928 Manno, Switzerland

Abstract

Polycationic tetraethyleneglycol dendrimers of low generation successfully deliver siRNA in human cells, with transfection efficiency comparable to that of Lipofectamine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NR/C5NR06757J

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