Anticancer drug impact on DNA – a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS-Reference-Cited by-同舟云学术

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Anticancer drug impact on DNA – a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS

Published:2019 Issue:8 Volume:21 Page:4162-4175
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Batista de Carvalho Ana L. M.¹²³⁴⁵^ORCID,Mamede Adriana P.¹²³⁴⁵^ORCID,Dopplapudi Asha⁶⁷⁸⁹¹⁰,Garcia Sakai Victoria⁶⁷⁸⁹¹⁰,Doherty James¹¹¹²⁸⁹¹⁰,Frogley Mark¹¹¹²⁸⁹¹⁰,Cinque Gianfelice¹¹¹²⁸⁹¹⁰,Gardner Peter¹³¹⁴¹⁵¹⁰^ORCID,Gianolio Diego¹¹¹²⁸⁹¹⁰,Batista de Carvalho Luís A. E.¹²³⁴⁵^ORCID,Marques M. Paula M.¹²³⁴⁵^ORCID

Affiliation:

1. Química-Física Molecular

2. Department of Chemistry

3. University of Coimbra

4. 3004-535 Coimbra

5. Portugal

6. ISIS Facility

7. STFC Rutherford Appleton Laboratory

8. Chilton

9. Didcot

10. UK

11. Diamond Light Source

12. Harwell Science and Innovation Campus

13. Manchester Institute of Biotechnology

14. University of Manchester

15. Manchester

Abstract

Complementary information on drug–DNA interplay has been achieved for Pt/Pd anticancer agents, by a combined QENS, SR-FTIR-ATR and EXAFS approach.

Funder

Fundação para a Ciência e a Tecnologia

FP7 Research infrastructures

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CP/C8CP05881D

Reference68 articles.

1. Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

2. Platinum Compounds: a New Class of Potent Antitumour Agents

3. Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

4. The resurgence of platinum-based cancer chemotherapy

5. The status of platinum anticancer drugs in the clinic and in clinical trials

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