Transition metal complexes as self-activating chemical nucleases: proficient DNA cleavage without any exogenous redox agents-Reference-Cited by-同舟云学术

Transition metal complexes as self-activating chemical nucleases: proficient DNA cleavage without any exogenous redox agents

Published:2023 Issue:21 Volume:52 Page:6961-6977
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Kumar Pramod¹^ORCID,Tomar Sunil²,Kumar Krishan³,Kumar Sushil⁴^ORCID

Affiliation:

1. Department of Chemistry, Mahamana Malviya College Khekra (Baghpat), C.C.S. University Meerut, India

2. Department of Zoology, Mahamana Malviya College Khekra (Baghpat), C.C.S. University Meerut, India

3. Department of Chemistry, Motilal Nehru College, South Campus University of Delhi, New Delhi, India

4. Department of Chemistry, School of Engineering, University of Petroleum and Energy Studies (UPES), Dehradun-248007, Uttarakhand, India

Abstract

This perspective presents DNA cleavage via self-activation based on transition metal complexes employing copper, zinc and iron with their mechanistic investigation.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00368J

Reference138 articles.

1. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

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5. N-Terminal Cu-Binding Motifs (Xxx-Zzz-His, Xxx-His) and Their Derivatives: Chemistry, Biology and Medicinal Applications

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