Beyond iron: metal-binding activity of the Pseudomonas quinolone signal-motif

Author:

Szamosvári Dávid1,Savchenko Viktoriia12,Badouin Natalie3,Böttcher Thomas1ORCID

Affiliation:

1. Faculty of Chemistry, Institute for Biological Chemistry & Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystems Science, University of Vienna, Josef-Holaubek-Platz 2 (UZA II), 1090 Vienna, Austria

2. Vienna Doctoral School in Chemistry (DoSChem), University of Vienna, Währinger Str. 42, 1090 Vienna, Austria

3. University of Konstanz, 78457 Konstanz, Germany

Abstract

The synthesis of two dimeric variants of the Pseudomonas quinolone signaling motif is reported, which, via colored and fluorescent metal complexes, informed the discovery of other metal complexes beyond iron(iii) for the natural product PQS.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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