Illuminating drug action by network integration of disease genes: a case study of myocardial infarction
Author:
Affiliation:
1. Department of Medicine
2. Brigham and Women's Hospital & Harvard Medical School
3. Boston
4. USA
Abstract
Illuminating the mechanisms of action of drugs used for myocardial infarction (MI) and the cardiovascular effects of non-MI drugs.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2016/MB/C6MB00052E
Reference68 articles.
1. Structure and dynamics of molecular networks: A novel paradigm of drug discovery
2. Drug Target Identification Using Side-Effect Similarity
3. Predicting new molecular targets for known drugs
4. Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation
5. Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference
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