Anti-drug antibody detection with label-free electrolyte-gated organic field-effect transistors

Author:

Sensi Matteo123ORCID,Berto Marcello123ORCID,Gentile Sara123,Pinti Marcello123,Conti Andrea45673ORCID,Pellacani Giovanni45673,Salvarani Carlo8910113,Cossarizza Andrea12923,Bortolotti Carlo Augusto123ORCID,Biscarini Fabio1231314ORCID

Affiliation:

1. Dipartimento di Scienze della Vita – Università di Modena e Reggio Emilia

2. 41125 Modena

3. Italy

4. Dipartimento Medicine Specialistiche

5. S.C. Dermatologia

6. Azienda Ospedaliero Universitaria di Modena

7. 41121 Modena

8. Unità Reumatologica

9. Università di Modena e Reggio Emilia

10. Azienda USL-IRCCS di Reggio Emilia

11. Modena

12. Dipartimento di Scienze Mediche e Chirurgiche Materno-Infantili e dell’Adulto

13. Center for Translational Neurophysiology

14. Istituto Italiano di Tecnologia

Abstract

The first label-free EGOFET immunosensor able to quantitatively detect anti-drug antibodies against Nivolumab, with a LOD of 100 fM.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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