A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S-Reference-Cited by-同舟云学术

A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S

Published:2019 Issue:14 Volume:10 Page:3956-3962
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hegedus Zsofia¹²³⁴⁵,Grison Claire M.¹²³⁴⁵^ORCID,Miles Jennifer A.¹²³⁴⁵,Rodriguez-Marin Silvia¹²³⁴⁵,Warriner Stuart L.¹²³⁴⁵^ORCID,Webb Michael E.¹²³⁴⁵^ORCID,Wilson Andrew J.¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry

2. University of Leeds

3. Leeds LS2 9JT

4. UK

5. Astbury Centre For Structural Molecular Biology

Abstract

An aromatic oligoamide foldamer acts as an α-helix mimetic and binds to the RNase S-protein resulting in restoration of its catalytic function.

Funder

FP7 Ideas: European Research Council

Engineering and Physical Sciences Research Council

Wellcome Trust

H2020 Marie Skłodowska-Curie Actions

Leverhulme Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC00374F

Reference57 articles.

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