Design, synthesis, and conformational analysis of 3-cyclo-butylcarbamoyl hydantoins as novel hydrogen bond driven universal peptidomimetics-Reference-Cited by-同舟云学术

Design, synthesis, and conformational analysis of 3-cyclo-butylcarbamoyl hydantoins as novel hydrogen bond driven universal peptidomimetics

Published:2018 Issue:4 Volume:16 Page:521-525
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bellucci M. C.¹²³⁴⁵,Frigerio M.⁶⁷⁸⁹¹⁰,Castellano C.⁶³⁴⁵,Meneghetti F.¹¹³⁴⁵,Sacchetti A.⁶⁷⁸⁹¹⁰,Volonterio A.⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Department of Food

2. Environmental and Nutritional Sciences

3. Università degli Studi di Milano

4. 20133 Milano

5. Italy

6. Department of Chemistry

7. Materials

8. and Chemical Engineering “Giulio Natta”

9. Politecnico di Milano

10. 20131 Milano

11. Department of Pharmaceutical Sciences

Abstract

3-cyclo-Butylcarbamoyl hydantoins are able to mimic α-helix and β-turn secondary structures as assessed by molecular modeling, NMR studies, and X-ray analysis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02680C

Reference23 articles.

1. Peptidomimetics for Receptor Ligands?Discovery, Development, and Medical Perspectives

2. Peptidomimetics, a synthetic tool of drug discovery

3. Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics

4. Tailoring Peptidomimetics for Targeting Protein–Protein Interactions

5. Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes

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