Hydrogel scaffold with substrate elasticity mimicking physiological-niche promotes proliferation of functional keratinocytes

Author:

Mogha Pankaj1234,Srivastava Ankita5234,Kumar Sushant5234,Das Sreya5234,Kureel Sanjay1234,Dwivedi Alka5234,Karulkar Atharva5234,Jain Nikita5234,Sawant Abhijeet6734,Nayak Chitra8934,Majumder Abhijit1234ORCID,Purwar Rahul5234ORCID

Affiliation:

1. Department of Chemical Engineering

2. Indian Institute of Technology Bombay

3. Mumbai

4. India

5. Department of Biosciences & Bioengineering

6. Department of Plastic Surgery

7. Topiwala National Medical College & B. Y. L. Nair Charitable Hospital

8. Department of Dermatology

9. B. Y. L Nair Ch. Hospital & T. N. Medical College

Abstract

High numbers of autologous human primary keratinocytes (HPKs) are required for patients with burns, wounds and for gene therapy of skin disorders.

Funder

Wellcome Trust

Bristol-Myers Squibb

Indian Institute of Technology Bombay

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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