An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their <i>N</i>-benzylated derivatives for inhibition of the activity of monoamine oxidases-Reference-Cited by-同舟云学术

An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases

Published:2023 Issue:36 Volume:13 Page:24925-24935
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Perumal Karuppaiah¹,Lee Jiseong²,Annes Sesuraj Babiola¹^ORCID,Ramesh Subburethinam¹^ORCID,Rangarajan T. M.³,Mathew Bijo⁴^ORCID,Kim Hoon²^ORCID

Affiliation:

1. Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613 401, Tamil Nadu, India

2. Department of Pharmacy, Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea

3. Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi, India

4. Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India

Abstract

The new pseudo-indoxyl compounds were synthesized by a designed simple metal-free methodology, and the lead compound 11f showed potent MAO-B inhibitory activity.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA03641C

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