Bisphosphine catalyzed sequential [3 + 2] cycloaddition and Michael addition of ynones with benzylidenepyrazolones via dual α′,α′-C(sp3)–H bifunctionalization to construct cyclopentanone-fused spiro-pyrazolones-Reference-Cited by-同舟云学术

Bisphosphine catalyzed sequential [3 + 2] cycloaddition and Michael addition of ynones with benzylidenepyrazolones via dual α′,α′-C(sp3)–H bifunctionalization to construct cyclopentanone-fused spiro-pyrazolones

Published:2018 Issue:48 Volume:16 Page:9461-9471
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Jiayong¹²³⁴⁵,Miao Zhiwei¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory and Institute of Elemento-Organic Chemistry

2. College of Chemistry

3. Nankai University

4. Tianjin 300071

5. People's Republic of China

Abstract

A sequential [3 + 2] cycloaddition and Michael addition reaction of ynones with benzylidenepyrazolones afforded cyclopentanone-fused spiro-pyrazolones catalyzed by DPPB via dual α′,α′-C(sp³)–H bifunctionalization.

Funder

National Natural Science Foundation of China

Nankai University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02675K

Reference67 articles.

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2. The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures

3. Front cover

4. Selected Synthetic Strategies to Spirocyclics

5. PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-Oxides

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