Nano-MoO3-mediated synthesis of bioactive thiazolidin-4-ones acting as anti-bacterial agents and their mode-of-action analysis using in silico target prediction, docking and similarity searching

Author:

Kumar Keerthy Hosadurga12345,Paricharak Shardul62789,Mohan Chakrabhavi Dhananjaya1011125,Bharathkumar Hanumantharayappa12345ORCID,Nagabhushana G. P.2345,Rajashekar Dinesh Koragere12345,Chandrappa Gujjarahalli Thimmanna2345,Bender Andreas6278,Basappa Basappa12345,Rangappa Kanchugarakoppal Subbegowda1011125

Affiliation:

1. Laboratory of Chemical Biology

2. Department of Chemistry

3. Bangalore University

4. Bangalore-560001

5. India

6. Centre for Molecular Informatics

7. Cambridge

8. UK

9. Division of Medicinal Chemistry

10. Department of Studies in Chemistry

11. University of Mysore

12. Mysore-570 006

Abstract

Thiazolidin-4-ones inhibit bacterial growth by potentially targeting the FtsK motor domain of DNA translocase ofSalmonella typhi.

Funder

University Grants Commission

Unilever

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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