Combined theoretical and experimental investigation of a DNA interactive poly-hydroxyl enamine tautomer exhibiting “turn on” sensing for Zn2+ in pseudo-aqueous medium-Reference-Cited by-同舟云学术

Combined theoretical and experimental investigation of a DNA interactive poly-hydroxyl enamine tautomer exhibiting “turn on” sensing for Zn2+ in pseudo-aqueous medium

Published:2021 Issue:44 Volume:45 Page:20806-20817
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Saha Urmila¹^ORCID,Mabhai Subhabrata²,Das Bhriguram³^ORCID,Kumar Gopinatha Suresh¹^ORCID,Brandão Paula⁴^ORCID,Dolai Malay⁵^ORCID

Affiliation:

1. Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700 032, W.B., India

2. Department of Chemistry, Mahishadal Raj College, Purba Medinipur 721628, W.B., India

3. Department of Chemistry, Vidyasagar University, Paschim Medinipur 721102, W. B., India

4. Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal

5. Department of Chemistry, Prabhat Kumar College, Purba Medinipur 721404, W.B., India

Abstract

Crystallographically established (solid state structure at 150 K temperature) synthesized enamine ligand (H4L) showed interconvertible equilibrium (ΔE = 7.37 kcal) of its tautomers, displayed zinc sensing and also found to exhibit DNA binding activity at the minor groove of double-stranded (ds) DNA.

Funder

Science and Engineering Research Board

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ03510J

Reference50 articles.

1. Imine or Enamine? Insights and Predictive Guidelines from the Electronic Effect of Substituents in H-Bonded Salicylimines

2. Schiff Bases from TRIS and ortho-Hydroxyarenecarbaldehydes: Structures and Tautomeric Equilibria in the Solid State and in Solution