Differentiation of prostate cancer from normal tissue in radical prostatectomy specimens by desorption electrospray ionization and touch spray ionization mass spectrometry

Author:

Kerian K. S.12134,Jarmusch A. K.12134,Pirro V.12134,Koch M. O.56574,Masterson T. A.56574,Cheng L.58574,Cooks R. G.12134

Affiliation:

1. Purdue University

2. Department of Chemistry and Center for Analytical Instrumentation Development

3. West Lafayette

4. USA

5. Indiana University School of Medicine

6. Department of Urology

7. Indianapolis

8. Department of Pathology and Laboratory Medicine

Abstract

Prostate cancer is distinguished reliably (>95% accuracy) from normal tissue using ambient spray ionization in a rapid diagnostic measurement.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference36 articles.

1. National Cancer Institute . Prostate Cancer, http://www.cancer.gov/cancertopics/types/prostateaccessed Jul 28, 2014, vol. 2014

2. Positive Surgical Margin and Perioperative Complication Rates of Primary Surgical Treatments for Prostate Cancer: A Systematic Review and Meta-Analysis Comparing Retropubic, Laparoscopic, and Robotic Prostatectomy

3. Positive Surgical Margins After Radical Prostatectomy: A Systematic Review and Contemporary Update

4. M. Che and D.Grignon, in Prostate Cancer: New Horizons in Research and Treatment, ed. M. Cher, A. Raz and K. Honn, Springer, US, 2002, vol. 81, pp. 3–17

5. Pathological and molecular aspects of prostate cancer

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