Electrochemical multicomponent [2+2+1] cascade cyclization of enaminones and primary amines towards the synthesis of 4-acylimidazoles-Reference-Cited by-同舟云学术

Electrochemical multicomponent [2+2+1] cascade cyclization of enaminones and primary amines towards the synthesis of 4-acylimidazoles

Published:2024 Issue:19 Volume:60 Page:2677-2680
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Mingxu¹,Gao Ying¹,Zhao Xiao-Jing¹^ORCID,Gao Lu¹,He Yonghui¹^ORCID

Affiliation:

1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes, State Ethnic Affairs Commission, School of Ethnic Medicine, Yunnan Minzu University Kunming, 650500, China

Abstract

Herein, we describe a challenging electrochemical multicomponent [2+2+1] cascade cyclization of enaminones with primary amines used for the synthesis of acylimidazoles under undivided electrolytic conditions at room temperature.

Funder

Applied Basic Research Key Project of Yunnan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D3CC06196E

Reference49 articles.

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4. Novel antifungals based on 4-substituted imidazole: solid-phase synthesis of substituted aryl sulfonamides towards optimization of in vitro activity

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