Identification of a fluorometabolite from Streptomyces sp. MA37: (2R3S4S)-5-fluoro-2,3,4-trihydroxypentanoic acid-Reference-Cited by-同舟云学术

Identification of a fluorometabolite from Streptomyces sp. MA37: (2R3S4S)-5-fluoro-2,3,4-trihydroxypentanoic acid

Published:2015 Issue:2 Volume:6 Page:1414-1419
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ma Long¹²³⁴,Bartholome Axel¹²³⁴,Tong Ming Him⁵⁶⁷⁸⁴,Qin Zhiwei⁵⁶⁷⁸⁴,Yu Yi⁹¹⁰¹¹¹²¹³,Shepherd Thomas¹⁴¹⁵⁴,Kyeremeh Kwaku⁶¹⁶¹⁷¹⁸,Deng Hai⁵⁶⁷⁸⁴,O'Hagan David¹²³⁴

Affiliation:

1. EaStChem School of Chemistry

2. University of St Andrews

3. St Andrews KY169ST

4. UK

5. Marine Biodiscovery Centre

6. Department of Chemistry

7. University of Aberdeen

8. Aberdeen AB24 3UE

9. Key Laboratory of Combinatory Biosynthesis and Drug Discovery (Ministry of Education)

10. School of Pharmaceutical Sciences

11. Wuhan University

12. Wuhan 430071

13. P. R. China

14. The James Hutton Institute

15. Dundee

16. University of Ghana

17. Legon

18. Ghana

Abstract

(2R3S4S)-5-Fluoro-2,3,4-trihydroxypentanoic acid (5-FHPA) has been discovered as a new fluorometabolite in the soil bacterium Streptomyces sp. MA37.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC03540B

Reference33 articles.

1. Fluorine in health care: Organofluorine containing blockbuster drugs

2. Catalytic Asymmetric Fluorination Comes of Age

3. Enzymatic Fluorination and Biotechnological Developments of the Fluorinase

4. Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya

5. Recent developments in enzymatic chlorination

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