Quercetin alleviates nanoparticle-induced osteolysis <i>via</i> deactivating pyroptosis-Reference-Cited by-同舟云学术

Quercetin alleviates nanoparticle-induced osteolysis via deactivating pyroptosis

Published:2023 Issue:13 Volume:11 Page:4616-4629
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Cheng Yu¹,Zhao Zhijian¹,Zhang Sheng²,Wu Yanglin³,Han Zhou⁴,Li Lijun⁵,Teng Yun¹,Lin Jun⁴^ORCID,Liu Naicheng¹,He Shuangjian⁶,Yang Huilin¹

Affiliation:

1. Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215006, China

2. Department of Cardiology, Tongren Hospital, School of Medicine, Shanghai Jiao Tong University, 200336, China

3. Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200092, China

4. Department of Orthopaedics, Suzhou Dushu Lake Hospital, Dushu Lake Hospital Affiliated to Soochow University, Medical Center of Soochow University, Suzhou, 215001 Jiangsu, China

5. Department of Orthopedics Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, People's Republic of China

6. Department of Orthopaedics, Suzhou Science & Technology Town Hospital, Suzhou 215153, China

Abstract

Quercetin regulates the balance of osteoclastogenic differentiation mediated by NLRP3 inflammasome activation, delaying the progression of wear particles-induced osteolysis.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00060E

Reference56 articles.

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5. A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response

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