Two new monofunctional platinum(ii) dithiocarbamate complexes:phenanthriplatin-type axial protection, equatorial-axial conformational isomerism, and anticancer and DNA binding studies

Author:

Imran Muhammad1234,Rehman Zia ur1234ORCID,Hogarth Graeme1567ORCID,Tocher Derek A.1867,Chaudhry Gul-e-Saba9101112ORCID,Butler Ian S.1131415,Bélanger-Gariepy Francine16171815,Kondratyuk Tamara192021

Affiliation:

1. Department of Chemistry

2. Quaid-i-Azam University

3. Islamabad

4. Pakistan

5. King's College London

6. London

7. UK

8. University College London

9. Institute of Marine Biotechnology

10. University Malaysia Terengganu

11. Kuala Terengganu

12. Malaysia

13. McGill University

14. Quebec

15. Canada

16. Département de Chimie

17. Université de Montréal

18. Montreal

19. University of Hawaii at Hilo

20. The Daniel K. Inouye College of Pharmacy

21. USA

Abstract

In this article, we describe syntheses, characterization and anticancer action of two platinum(ii) dithiocarbamate complexes (1and2) that show quinoplatin- and phenanthriplatin-type axial protection of the Pt-plane.

Funder

The World Academy of Sciences

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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