Identification of a novel cytochrome P450 17A1 enzyme and its molecular engineering-Reference-Cited by-同舟云学术

Identification of a novel cytochrome P450 17A1 enzyme and its molecular engineering

Published:2023 Issue:2 Volume:13 Page:548-557
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Chen Kexin¹²,Liu Chao¹²,Zhang Xian¹²,Xu Zhenghong¹^ORCID,Shao Minglong¹²,Yang Taowei¹²,Rao Zhiming¹²^ORCID

Affiliation:

1. Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi, Jiangsu, 214122, China

2. Laboratory of Applied Microorganisms and Metabolic Engineering, School of Biotechnology, Jiangnan University, Wuxi 214122, China

Abstract

Progesterone-17α-hydroxylase (CYP17A) could transform progesterone to 17α-hydroxyprogesterone (17-HP).

Funder

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CY/D2CY01605B

Reference40 articles.

1. Enhancement of 17α-hydroxyprogesterone production from progesterone by biotransformation using hydroxypropyl-β-cyclodextrin complexation technique

2. Microbial steroid transformations: current state and prospects

3. Identification of bottlenecks in 4-androstene-3,17-dione/1,4-androstadiene-3,17-dione synthesis by Mycobacterium neoaurum JC-12 through comparative proteomics

4. Cytochromes P450 as versatile biocatalysts

5. New Insights on Steroid Biotechnology

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Production of 17α-hydroxyprogesterone using an engineered biocatalyst with efficient electron transfer and improved 5-aminolevulinic acid synthesis coupled with a P450 hydroxylase;International Journal of Biological Macromolecules;2024-07

2. Novel cytochrome P450s for various hydroxylation of steroids from filamentous fungi;Bioresource Technology;2024-02