Simultaneous determination of a broad range of cardiovascular drugs in plasma with a simple and efficient extraction/clean up procedure and chromatography-mass spectrometry analysis-Reference-Cited by-同舟云学术

Simultaneous determination of a broad range of cardiovascular drugs in plasma with a simple and efficient extraction/clean up procedure and chromatography-mass spectrometry analysis

Published:2014 Issue:38 Volume:4 Page:19629-19639
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Liu Lei¹²³,Wen Yabin⁴²³,Liu Kangning¹²³,Sun Liang¹²³,Lu Yaxin¹²³,Yin Zheng¹²³

Affiliation:

1. College of Pharmacy & State Key Laboratory of Elemento-Organic Chemistry

2. Nankai University

3. Tianjin 300071, PR China

4. College of Life Science

Abstract

A simple, easy to use and efficient method was described for simultaneous determination of ten cardiovascular drugs with a broad range of physicochemical properties in rat plasma via online SPE and HPLC-MS/MS.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA01045K

Reference39 articles.

1. Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies

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4. A review of current trends and advances in modern bio-analytical methods: Chromatography and sample preparation

5. Recent advances in SPME techniques in biomedical analysis

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