Structure-based design and analysis of SuFEx chemical probes
Author:
Affiliation:
1. Center for Protein Degradation
2. Dana-Farber Cancer Institute
3. Boston
4. USA
5. Departments of Chemistry and Molecular Medicine
6. The Scripps Research Institute
7. La Jolla
Abstract
Binding site microenvironments determine the context-dependent reactivity of sulfur(vi) fluoride-containing probes.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/MD/C9MD00542K
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5. Sulfonyl Fluorides as Inhibitors of Esterases. III. Identification of Serine as the Site of Sulfonylation in Phenylmethanesulfonyl α-Chymotrypsin*
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