PEG-containing ruthenium phthalocyanines as photosensitizers for photodynamic therapy: synthesis, characterization and in vitro evaluation-Reference-Cited by-同舟云学术

PEG-containing ruthenium phthalocyanines as photosensitizers for photodynamic therapy: synthesis, characterization and in vitro evaluation

Published:2017 Issue:29 Volume:5 Page:5862-5869
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Teles Ferreira Joana¹²³⁴⁵,Pina João⁶⁷⁸⁹¹⁰,Alberto Fontes Ribeiro Carlos¹¹¹²⁸¹³¹⁰,Fernandes Rosa¹¹¹²⁸¹³¹⁰^ORCID,Tomé João P. C.⁵¹⁴¹⁵¹⁰¹⁶^ORCID,Rodríguez-Morgade M. Salomé¹²³⁴¹⁷^ORCID,Torres Tomás¹²³⁴¹⁷^ORCID

Affiliation:

1. Departamento de Química Orgánica

2. Universidad Autónoma de Madrid (UAM)

3. 28049 Madrid

4. Spain

5. Department of Chemistry and QOPNA

6. CQC

7. Department of Chemistry

8. University of Coimbra

9. Coimbra

10. Portugal

11. IBILI

12. Faculty of Medicine

13. 3000-548 Coimbra

14. University of Aveiro

15. 3810-193 Aveiro

16. Centro de Química Estrutural

17. Institute for Advanced Research in Chemical Sciences (IAdChem)

Abstract

Three ruthenium(ii) phthalocyanines functionalized at their axial positions with 4–12 PEG chains bearing hydroxy, amino and ether terminal groups were synthesized and studied as PDT agents against bladder cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB00958E

Reference46 articles.

1. Pharmaceutical development, composition and quantitative analysis of phthalocyanine as the photosensitizer for cancer photodynamic therapy

2. Photodynamic therapy for cancer

3. Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

4. Basic principles of photodynamic therapy

5. Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia

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