Dual-light defined <i>in situ</i> oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel-Reference-Cited by-同舟云学术

Dual-light defined in situ oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel

Published:2023 Issue:9 Volume:11 Page:3180-3196
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Liu Huijie¹²,Li Qun¹²,Xu Yingying¹²,Sun Yue³,Fan Xin¹,Fang Huaqiang²,Hu Binbin²,Huang Li²,Liao Lan¹,Wang Xiaolei³²^ORCID

Affiliation:

1. The Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. China

2. The National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. China

3. College of Chemistry and Chemical Engineering of Nanchang University, Nanchang University, Nanchang, Jiangxi, 330088, P.R. China

Abstract

ZPTA-G/HMA can treat oral mucosal lesions by in situ anchoring to wet mucosa surface for hemostasis and the production of ROS for anti-bacteria under GL irradiation, as well as by enhanced anti-inflammation for promoting healing with NIR irradiation.

Funder

Key Research and Development Program of Jiangxi Province

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01721K

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1. Crosstalk between the oral microbiota, mucosal immunity, and the epithelial barrier regulates oral mucosal disease pathogenesis