Dopamine-modified TiO2 monolith-assisted LDI MS imaging for simultaneous localization of small metabolites and lipids in mouse brain tissue with enhanced detection selectivity and sensitivity

Author:

Wu Qian12345,Chu James L.6234,Rubakhin Stanislav S.12345ORCID,Gillette Martha U.62345,Sweedler Jonathan V.12345ORCID

Affiliation:

1. Department of Chemistry

2. University of Illinois at Urbana-Champaign

3. Urbana

4. USA

5. Beckman Institute

6. Department of Cell and Developmental Biology

Abstract

A dopamine-modified TiO2 monolith was developed to assist LDI MS imaging for small metabolites and lipids simultaneously with enhanced sensitivity.

Funder

National Institute on Drug Abuse

University of Illinois at Urbana-Champaign

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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