Fluorescent imaging using novel conjugated polymeric nanoparticles-affimer probes in complex <i>in vitro</i> models of colorectal cancer-Reference-Cited by-同舟云学术

Fluorescent imaging using novel conjugated polymeric nanoparticles-affimer probes in complex in vitro models of colorectal cancer

Published:2023 Issue:30 Volume:15 Page:12476-12480
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Jolugbo Precious¹^ORCID,Willott Thomas¹,Lin Wei-Hsiang²,Maisey Thomas¹^ORCID,O'Callaghan Dermott³,Green Mark A.³⁴^ORCID,Jayne David G.¹,Khot M. Ibrahim¹^ORCID

Affiliation:

1. Leeds Institute of Medical Research at St James’, School of Medicine, St James University Hospital, University of Leeds, Leeds, LS9 7TF, UK

2. Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK

3. Stream Bio Ltd, Alderley Park, Nether Alderley, Cheshire, SK10 4TG, UK

4. Department of Physics, Faculty of Natural, Mathematical & Engineering Sciences, King's College London, Strand, London, WC2R 2LS, UK

Abstract

CPN510-CEA-Af is a targeted fluorescent probe that demonstrated a high fluorescence signal when bound to 2D monolayer and 3D spheroidal cell culture of colorectal cancer cells.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D3NR02160B

Reference37 articles.

1. Colorectal cancer

2. Recent updates in the surgical treatment of colorectal cancer

3. Clinicopathological Features of Stage I–III Colorectal Cancer Recurrence Over 5 Years After Radical Surgery Without Receiving Neoadjuvant Therapy: Evidence From a Large Sample Study

4. Optical Image-Guided Cancer Surgery: Challenges and Limitations

5. Fluorescence-Guided Surgery

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